Zebra ZD421 vs Zebra ZD621
Side-by-side comparison of barcode printers specs, hardware, and features to help you pick the right one for your use case.

Zebra's next-generation desktop printer with built-in Print DNA smart software suite, multiple connectivity options, easy operation and enhanced security.

Zebra premium desktop printer, up to 203 mm/s print speed, supports 5-inch media rolls, ideal for medium to high-volume labeling.
Which one should you pick?
Both Zebra ZD421 and Zebra ZD621 are proven barcode printers options sold through JUNJI as an authorized distributor. Zebra ZD421 suits users who prioritize enterprise reliability and global service network. Zebra ZD621 is a better fit for large-scale deployments needing vendor parity. Request a quote and we'll match you to the exact configuration for your workflow.
Full spec comparison
| Specification | Zebra ZD421 | Zebra ZD621 |
|---|---|---|
| Print Method | Direct Thermal / Thermal Transfer | Direct Thermal / Thermal Transfer |
| Resolution | 8 dots/mm / 12 dots/mm | 8 dots/mm / 12 dots/mm |
| Print Speed | 6 ips / 4 ips | 8 ips / 6 ips |
| Print Width | 203 dpi: 104 mm (4.09"); 300 dpi: 108 mm (4.27") | 203 dpi: 104 mm (4.09"); 300 dpi: 108 mm (4.27") |
| Max Print Length | 991 mm (39") | 991 mm (39") |
| Memory | 256 MB SDRAM / 512 MB Flash | 256 MB SDRAM / 512 MB Flash |
| Sensors | Multi-point transmissive + full-width reflective + print head opening sensor | Multi-point transmissive + full-width reflective + print head opening + media dancer (dancer) to ensure print quality |
| Media Types | Roll or folded sheet: labels (die-cut or continuous, thermal or thermal transfer)/tags/receipt paper (continuous, thermal)/wristbands | Roll or folded sheet: label/tag (die-cut or continuous, thermal or thermal transfer)/receipt paper/wristband |
| Media Width | ZD421t: 15 – 112 mm (0.585 – 4.41"); ZD421c: 15 – 118 mm (0.585 – 4.65"); ZD421d: 15 – 108 mm (0.585 – 4.25") | ZD621t: 15 – 118 mm (0.585 – 4.65"); ZD621d: 15 – 108 mm (0.585 – 4.25") |
| Media Roll OD | Max 127 mm (5") | Max 127 mm (5") |
| Media Core | Standard 12.7 / 25 mm (0.5" / 1"); optional adapter 38.1 / 50.8 / 76 mm (1.5" / 2" / 3") | Standard 12.7 / 25 mm (0.5" / 1"); optional adapter 38.1 / 50.8 / 76 mm (1.5" / 2" / 3") |
| Ribbon Length | Roll: 300 m or 74 m; Cartridge: 74 m | 300m or 74m |
| Ribbon Width | Roll: 33.8 – 109.2 mm (1.33" – 4.3"); Cartridge: 109.2 mm (4.3") | 33.8 – 109.2 mm (1.33" – 4.3") |
| Interface | Standard USB 2.0 + USB Host + Bluetooth LE; optional 10/100 Ethernet + RS-232 Serial + Wi-Fi 802.11ac + Bluetooth 4.1 | Standard 10/100 Ethernet + RS-232 Serial + USB 2.0 + USB Host + Bluetooth LE; optional Wi-Fi 6 (802.11ax) + Bluetooth 5.3 or Wi-Fi 5 (802.11ac) + Bluetooth 4.2 |
| Programming Language | ZPL II / EPL2 / Link-OS | ZPL II / EPL2 / Link-OS |
| Certification | ENERGY STAR, meets Energy Efficiency Level VI | ENERGY STAR, meets Energy Efficiency Level VI |
| Power | External transformer 100-240 VAC 50-60 Hz, output 24 VDC 2.5A | External transformer 100-240 VAC 50-60 Hz, output 24 VDC 3.125A |
| Weight | Thermal transfer: 2.05 kg; Thermal: 1.35 kg; Ribbon cartridge: 2.3 kg | Thermal transfer: 2.5 kg; thermal: 1.6 kg |
| Dimensions | Thermal transfer: 267 × 202 × 189 mm; Thermal: 220.8 × 177.5 × 150.7 mm; Ribbon cartridge: 254 × 202 × 177 mm | Thermal transfer: 267 × 202 × 192 mm; thermal: 220 × 177 × 151 mm |
| Display | — | Optional 4.3" full-color touch LCD (480 × 272) + 5 status icons + 3 buttons (standard for Healthcare / RFID models) |
Differences highlighted. Data source: JUNJI product catalog (20 spec rows compared).
